Posted to MedZilla on 5/19/2019

Takeda Pharmaceuticals

US-CA, Scientist II Medicinal Chemistry R0008261-MZ


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Job Description

Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as a Scientist II, Medicinal Chemistry in our San Diego.

Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As a Scientist II working on the GI Chemistry team, you will be empowered to develop novel and efficient strategies and address issues of target potency, selectivity and in vivo efficacy. A typical day will include:


Contributes to the design and synthesis of small-molecules for drug discovery projects in order to advance those programs into preclinical development


  • Develops novel and efficient synthesis strategies and coordinates research strategies and activities with team members
  • Designs synthetic targets for lead discovery and optimization to address issues of target potency, selectivity, animal pharmacokinetics, and in vivo efficacy
  • Utilizes contemporary structure-based methods, structure-activity relationships, and medicinal chemistry principles in the proposal and execution of innovative chemistry strategies
  • Conducts the synthesis of complex target molecules
  • Designs viable synthetic routes and performs literature searches in support of research
  • Creates relevant intellectual property for the company and contributes to patent authorship
  • May mentor Research Associates and/or Intern


Technical/Functional (Line) Expertise

  • Demonstrates broad understanding of modern synthetic chemistry.
  • May act as a scientific resource in designing synthetic routes to key target compounds
  • Demonstrates effective project engagement skills


  • Capable of setting chemistry strategies, priorities and managing activities to deliver on objectives and milestones.
  • May mentor Research Associates and/or Intern. May lead a small team working together to drive lead optimization. May manage CRO chemistry resources.
  • Proven track record of scientific contributions in synthetic/medicinal chemistry as evidenced by quality and quantity of publications.

Decision-making and Autonomy

  • Independently manages workload and expectations
  • Scientifically independent
  • May influence decision making within the department


  • Positive can-do attitude with excellent communication and collaboration skills and ability to work with cross-functional scientists.
  • Ability to clearly and concisely conveys ideas and opinions


  • Highly motivated and flexible with ability to work in fast-paced environment.
  • Ability to provide novel creative solutions to challenging problems.
  • Desire to learn and tackle new challenges and initiatives.


  • PhD degree in a scientific discipline with 2+ years experience , or
  • MS with 8+ years experience, or
  • BS with 10+ years experience


  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement
  • Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

Empowering Our People to Shine

Learn more at

No Phone Calls or Recruiters Please.



San Diego, CA

Worker Type


Worker Sub-Type


Time Type

Full time

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