The successful candidate will join a team of scientists in an exciting fast paced environment engaged in multiple concurrent therapeutic biologic discovery and engineering projects. The candidate will independently perform complex research lab assignments contributing to the discovery and engineering of therapeutic biologics, including antibodies, VHH, alternative platforms, and multispecific targeting molecules. The candidate will apply and build on previous related experience to contribute to the experimental design and execution of active campaigns. As part of the Biologics Engineering group, the candidate will actively contribute to the team meetings, communicating experiments and results with project team members.
- Independently conducts complex experiments within a project scope, exercising judgement to evaluate a variety of technical factors, and obtain optimum solutions
- Independently provides work group with technical guidance and problem resolution related to methods, procedures and processes
- Utilizes assigned literature to increase knowledge base and implement improvements
- Expected to organize time and plan specifics of project related work with oversight from manager or project representative
- Prepares and presents technical information at department meetings
- Troubleshoots non-routine methods, instrumentation, or software issues and recommends systems, processes, or changes within project scope to meet objectives. Proactively seeks help on issue
- Demonstrates in-depth knowledge of currently assigned research methods
- Understands why a series of experiments is selected
- Demonstrates basic knowledge of science/technology outside specific discipline
- Recognizes problems and considers the significance of irregularities
EDUCATION AND SKILLS:
- BS in a scientific discipline (or equivalent) with 4+ years experience, or MS in a scientific discipline with 1+ years experience
- Demonstrates in-depth knowledge of currently assigned research methods including:
- Antibody discovery through hybridoma, phage, and/or yeast platforms
- Experience with mammalian tissue, bacteria, and yeast culture
- Molecular biology techniques including; PCR, DNA/RNA purification methods, cloning and sequencing.
- Experience with fluorescence-activated cell sorter and magnetic-activated cell sorter is desired
- Experience in high-throughput antibody sequence isolation, reformatting, recombinant antibody expression, and antibody purification is desired.
- Manual dexterity required to operate office and lab equipment
- Carrying, handling and reaching for objects up to 25 lbs
- Prolonged standing and/or sitting
- Exposure to hazardous/toxic/dangerous chemicals