Posted to MedZilla on 2/23/2019


Takeda Pharmaceuticals

US-CA, Scientist I - Medicinal Chemistry R0006255-MZ


 
 

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Job Description

OBJECTIVES:

Provides theoretical/conceptual input to the design, development and execution of well-defined specific projects and within the area of expertise.

ACCOUNTABILITIES:

  • Develops novel and efficient synthesis strategies and coordinates research strategies and activities with team members
  • Designs synthetic targets for lead discovery and optimization to address issues of target potency, selectivity, animal pharmacokinetics, and in vivo efficacy
  • Utilizes contemporary structure-based methods, structure-activity relationships, and medicinal chemistry principles in the proposal and execution of innovative chemistry strategies
  • Conducts the synthesis of complex target molecules
  • Designs viable synthetic routes and performs literature searches in support of research
  • Creates relevant intellectual property for the company and contributes to patent authorship
  • Contributes to the authorship of scientific manuscripts, frequently as principal author
  • Maintains a current understanding of the synthetic literature and methodology, as well as the scientific literature related to a specific drug discovery project
  • Keeps an accurate, comprehensible, concise notebook in accordance with company policy
  • Influences the course of projects
  • With general guidance, learns standards and levels of expectations for routine work; designs experimental strategies
  • Learns company's discovery process
  • Identifies routine obstacles to progress; solves a variety of problems
  • Supports at least one project of defined scope and moderate complexity
  • Represents own research to senior leadership, or for scientific collaborations, or a national scientific conference

EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS:

  • Ph.D. in Chemistry, OR
  • MS in Chemistry with minimum 6 years of relevant chemistry research experience, OR
  • BS in Chemistry with minimum 8 years of relevant chemistry research experience
  • Clear general knowledge of chemistry
  • Diverse practical experience in synthetic organic chemistry
  • Clear understanding of experimental design
  • Clear understanding of reaction mechanism
  • Good understanding of basic biochemical and biological principles
  • High level of professional expertise in modern laboratory and analytical methods
  • Has demonstrated independent thought/creativity in science
  • Ability to present work formally to internal scientific reviews
  • Ability to convey ideas in an experimentally detailed yet scientifically concise manner
  • Excellent communication and multitasking skills
  • Expert knowledge of applicable lab equipment
  • Possesses a high degree of scientific discretion/intuition
  • Proficiency with chemistry drawing software (e.g., Chemdraw) and MS office applications

    LICENSES/CERTIFICATIONS:

  • None required

    PHYSICAL DEMANDS:

  • Manual dexterity required to operate standard laboratory and office equipment
  • Carrying, handling and reaching for objects
  • Exposure to hazardous/toxic/dangerous chemicals
  • Prolonged standing and/or sitting

TRAVEL REQUIREMENTS:

  • May travel to various domestic conferences or client sites, including overnight trips
  • Some international travel may be required
  • Requires up to 2% travel

Locations

San Diego, CA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time


Please visit our website at takedajobs.com

 
 


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