Posted to MedZilla on 12/5/2019

Takeda Pharmaceuticals

US-MA, Manager, Vaccine Technical Operations R0012371-MZ


By clicking the Apply button, I understand that my employment application process with Takeda will commence and that I agree with Takeda s Privacy Notice, Privacy Policy and Terms of Use.

Job Description


The Manager, Vaccine Technical Operations will be responsible for:

  • Providing technical oversight support as required for sterile process operations being carried out at Takeda s network of manufacturing partners
  • Supporting implementation of manufacturing and quality systems (such as change controls, deviations, etc.) in collaboration with internal and external partners.
  • Working with Development and Operations Teams to plan and manage process improvements, scale-up, technical transfers and life-cycle management.
  • Developing and implementing manufacturing solutions to enhance quality, cost and robustness of vaccine manufacturing processes


  • Provide scientific and technical support of commercial manufacturing at partners to support corporate goals for supply strategies, productivity, quality, and compliance.
  • Provide ongoing technical support for change control, deviation investigations and CAPA management as required during development and commercial manufacturing
  • Partner with internal and external stakeholders communicate, escalate and resolve program issues both within Takeda and with external manufacturing partners
  • Partner with engineering to provide process inputs for process fit assessments and to define process requirements for new manufacturing facilities.
  • Working cross-functionally, develop robust proposals for scale-up and technology transfer of vaccine products, and for life-cycle management changes.
  • Lead cross-functional teams for engineering, qualification and validation of new and existing vaccine manufacturing facilities / processes and technology transfers
  • Build partnerships in the areas of engineering and process equipment to drive awareness of new technologies for best in class manufacturing operations.


  • BS with a minimum of 5 years experience or MS with a minimum of 3 years experience in start-up, tech transfer, and/or sustaining cGMP for commercial sterile process operations in vaccines or biopharmaceuticals.
  • Scientific and technical knowledge regarding CIP/SIP, formulation processes, aseptic filling, isolator technology, lyophilization and visual inspection.
  • Demonstrated expertise in process transfer for drug product operations, including formulation/filling, lyophilization and/or visual inspection
  • Experience in single use technologies, and the ability to manage vaccine-specific nuances and strategies. Experience working with live viruses is a plus
  • A self-starter and team player who can balance the needs of an entrepreneurial environment with the requirements of structured product development
  • Proven ability to work with efficiency across multiple project teams and business functions in a matrix environment.
  • Able to lead and manage technical teams, serve as a partner and influence others. Demonstrated cross-functional team experience.
  • Willingness to travel
  • German language considered a plus.


  • 20% domestic and international

Learn more at

No Phone Calls or Recruiters Please.



Cambridge, MA

Worker Type


Worker Sub-Type


Time Type

Full time

Please visit our website at


* If a direct employer requests that you go to their web site and complete your application there in order to be
  considered, please do so. Applications for all positions are subject to each employer's specific requirements.