Posted to MedZilla on 9/22/2019


Takeda Pharmaceuticals

US-MA, Scientist 1, DMPK R0011697-MZ


 
 

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Job Description

Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as a Scientist 1, DMPK in our Cambridge office.

At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Futureto people around the world.

Here, you will be a vital contributor to our inspiring, bold mission.

Primary Duties

The Drug Metabolism and PK Scientist/Senior Scientist will be responsible for providing pharmacokinetic (PK), and PK / pharmacodynamic (PD) correlation analysis and reporting expertise for multiple drug discovery and development programs from a variety of therapeutic areas spanning discovery/early development and continuing through late stage / post marketing clinical development. The individual will be responsible for generating PK reports and relevant sections of non-clinical / clinical protocols, and relevant sections of Regulatory filings. The individual will work closely with drug safety, quantitative solution, clinical pharm, and discovery and development colleagues to generate study designs and integrate data leading to the establishment of clinical dose regimens for novel therapeutics. The individual will also represent the DMPK function on program teams. The individual will liaise between DMPK and relevant R and D Departments / Groups to achieve discovery and development objectives.

Responsibilities

  • Serve as a DMPK program team representative on discovery, early and global development projects. Liaise between relevant functional areas to advance project team goals
  • Responsible for generation of quantitative/systems pharmacology, PK, PBPK and PK/PD modeling and simulation to support candidate nomination and clinical dose projections. Contribute to design of clinical protocols for early and global development projects.
  • Oversee the design and conduct of nonclinical studies.
  • Ability to provide Pharmacokinetic and Pharmacodynamic expertise and representation for Nonclinical Development on multidisciplinary discovery and development project teams and with regulatory agencies.
  • Ability to develop interdisciplinary collaborations and ensure that key nonclinical data, information and priorities are integrated into overall drug or biologic project team strategy

Educations and experience requirements

  • Ph.D in pharmaceutical sciences or related disciplines with 2+ year industry experience.
  • Experience PK/PD software such as Phoenix, Simcyp
  • A broad understanding of the drug development process and the ability to design and implement PK/PD assessments within an integrated drug development organization.
  • Experience with gene therapy or therapeutic protein drug development is preferred

WHAT TAKEDA CAN OFFER YOU:

  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

    Empowering Our People to Shine

    Discover more at takedajobs.com

    No Phone Calls or Recruiters Please.

    #LI-JT1

Locations

Boston, MA

Worker Type

Employee

Worker Sub-Type

Regular

Time Type

Full time


Please visit our website at takedajobs.com

 
 


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