This position will be responsible for providing support with all aspects of formulation, dosing (oral and parenteral routes), sample collection and clinical monitoring of efficacy, pharmacodynamic, pharmacokinetic and exploratory toxicology evaluations. Efficacy models will include mice and rat models of GI and immunology. This individual will interact closely with other biologists, medicinal and bioanalytical chemists. Responsibilities will also include assisting in animal surgeries and support development/validation of animal models for efficacy established by TCAL. You will be expected to have good computer skills; Microsoft word, excel, graphical presentation of data and Powerpoint slide presentations. Weekend work may be required. Additionally, this individual will assist with the selection and preparation of suitable formulations for in vivo rodent model testing across all research programs.
- Performs in vivo rodent dosing, rodent surgery and tissue collection.
- Performs data analysis and present results when necessary
- Assists in vitro assays (MSD, ELISA)
- Prepares samples for external shipments
EDUCATION, EXPERIENCE, KNOWLEDGE AND SKILLS:
- Undergraduate student in good academic standing with a focus in immunology, pharmaceutical science, or a related biological or chemical science field (Second or Third year students preferred)
- Students must be legally authorized to work in the United States.
- Expected hours: 10 - 20 hours while school is in session; up to 40 hours during school breaks
- Applicants must be highly motivated, self-starters with excellent oral and written communication.
- Applicants must be willing to work with rodents as well as human tissues, cells, and fluids.
- Candidate should have a strong interest and understanding of Immunololgy and Gastroenterology Biology.
- Previous experience with each of the following is preferred but not required: animal handling and dosing, RNA preparation/sequencing, qPCR, ELISA, MSD, and IHC.
- Potential exposure to cold temperatures, loud noises, reactive chemicals and possible rodent allergens.