Posted to MedZilla on 1/20/2018


Takeda Pharmaceuticals

US-MA, Antibody Discovery Senior Scientist I 1703323-MZ


 
 

Are you looking for a patient-focused company that will inspire you and support your career? If so, be empowered to take charge of your future at Takeda. Join us as an Antibody Discovery Senior Scientist I in our Cambridge office.

Here, everyone matters and you will be a vital contributor to our inspiring, bold mission. As an Antibody Discovery Senior Scientist I working on the Protein Sciences team, you will be empowered to establish antibody discovery approaches and methodologies and develop therapeutic antibodies for Immuno-Oncology , and a typical day will include:

POSITION OBJECTIVES:
As a key member of the Antibody Technologies team and a skillful bench scientist, to independently establish antibody discovery approaches and methodologies to enable the discovery and development of therapeutic antibodies for Immuno-Oncology and Takeda s core therapeutic areas.

POSITION ACCOUNTABILITIES:
  • To be a key member of a team focusing on antibody discovery for the development of antibody-based therapeutics.
  • To independently design, develop and execute methodologies and workflows for hybridoma and B-cell-cloning for fully human antibody discovery and screening, high-throughput antibody sequence isolation, reformatting, recombinant antibody expression, and lead antibody identification.
  • To establish information tracking and material management systems associated with the antibody discovery processes, and to provide material for in depth antibody evaluation and selection.
  • To document protocols and foster sharing of expertise as a scientific resource for others in the organization based on extensive knowledge of antibodies and antibody discovery.
  • This individual needs to work closely with the protein expression and purification teams to develop optimal screen reagents, and will need to keep effective communications in a multi-functional team setting.

EDUCATION, EXPERIENCE, BEHAVIOURAL COMPETENCIES AND SKILLS:

  • PhD in Immunology, cell biology, molecular biology, protein/antibody engineering or related fields and with at least 5-6+ years industry experience, or equivalent.
  • Must have in-depth knowledge and expertise with independently designing workflows for hybridoma and B-cell-cloning for fully human antibody discovery and screening.
  • Experience in high-throughput antibody sequence isolation, reformatting, recombinant antibody expression, and lead antibody identification is needed.
  • This individual must be self-motivated, with a proven record of working in a multi-functional team setting, and is effective in sharing learning and expertise.
  • Strong skills in communication, problem solving, cross-function collaboration, planning, documentation, and organization are required.
  • Experience with na ve, immunized and/or synthetic antibody library design

  • Experience with in vitro affinity maturation methods
  • Experience working with high throughput liquid handlers
  • Experience with multicolor flow cytometry desired
TRAVEL REQUIREMENTS:
  • < 5% of time as required to support business needs

WHAT TAKEDA CAN OFFER YOU:

  • 401(k) with company match and Annual Retirement Contribution Plan
  • Tuition reimbursement
  • Company match of charitable contributions
  • Health & Wellness programs including onsite flu shots and health screenings
  • Generous time off for vacation and the option to purchase additional vacation days
  • Community Outreach Programs

Empowering Our People to Shine


Learn more at takedajobs.com.

Takeda is an EEO employer of minorities, women, disabled, protected veterans, and considers qualified applicants with criminal histories in accordance with applicable laws. For more information, visit http://www.takeda.us/careers/EEO_Policy_Statement.aspx

No Phone Calls or Recruiters Please.

#LI-JT1


Schedule
Full-time

Please visit our website at takedajobs.com

 
 


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