Posted to MedZilla on 4/25/2017


Takeda Pharmaceuticals

US-MA, Scientific Director, Vaccine Discovery - Vaccine Busines Unit 1603178-MZ


 
 

OBJECTIVES:
  • Conceive, design, and direct the execution of vaccine discoveryprograms
  • Lead team of Ph.D. scientists and research associates to execute and complete vaccine discovery project objectives
  • Support existing vaccine projects in pre-clinical and clinical development including development of lab-scale processes, analytical methods for vaccine characterization and preclinical and clinical immunogenicity and efficacy evaluation.
  • Author reports to support regulatory filings.
  • Establish and direct collaborative projects with other Takeda functions, academic and industry collaborators

ACCOUNTABILITIES:

  • Lead discovery activities for one or more project to develop candidate live-attenuated, inactivated, or recombinant vaccines through pre-clinical evaluation.
  • Effectively manage a team of Ph.D. scientists and research associates, including promoting a culture of team accomplishment and providing career development.
  • Design program and lead team to execute complex vaccine development activities in support of regulatory filings for new vaccine candidates or those already in clinical development, including:
  • Lab-scale processes for seed virus generation and antigen production.
  • Analytical method development to quantitate potency and characterize vaccine components
  • Immunogenicity and efficacy models and immune assays to quantify immune responses in pre-clinical studies.
  • Novel immunogenicity and virology assays for exploratory clinical endpoints
  • Analyze, interpret and summarize complex data and contribute to project decisions.
  • Propose, establish and lead collaborative projects with academic and corporate collaborators or CROs.
  • In collaboration with clinical development, design and execute R&D studies to characterize human clinical immune responses to candidate vaccines in development.
  • Collaborate with process development and CMC in the transfer of analytical methods and vaccine candidates.
  • Contribute as Discovery representative on one or more Global Project Teams
  • Present project plans, status and results in internal and external meetings and publications.
  • Other duties as required.

Qualifications

EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:

  • Ph.D. in a scientific discipline with a minimum of 16 years vaccine development experience , MS in a scientific discipline with a minimum of 18 years vaccine development experience, or a BS in a scientific discipline with a minimum of 20 years vaccine development experience.
  • Proven ability to design and develop viral vaccines, including scientific accomplishment in virology, molecular biology, immunology or related field.
  • Scientific management experience, including demonstrated experience managing laboratory personnel in a team environment and a working knowledge of scientific project management.
  • Significant industry experience and working knowledge of GLP practices.
  • Well connected in the vaccine research and development field, with proven track record of establishing and managing collaborative projects.
  • Exemplary oral and written communication skills
  • Compliance with Takeda safety practices and standard operating procedures.
  • Exhibit and promote Takeda Core Competencies.


LICENSES/CERTIFICATIONS:
  • Comply with institutional certifications and requirements in a BSL-2 environment, including shipping regulations for infectious agents.
PHYSICAL DEMANDS:
  • Manual dexterity required to operate office equipment (i.e. computers, phones, etc.).
  • Typical office and laboratory bending, stooping, lifting requirements apply.
TRAVEL REQUIREMENTS:
  • Position requires up to 25% travel
  • International travel will be required

we are driven to improve people's lives

www.takedajobs.com

Takeda is an EEO employer of minorities, women, disabled, protected veterans. For more information, visithttp://www.takeda.us/careers/EEO_Policy_Statement.aspx

No Phone Calls or Recruiters Please.


Schedule
Full-time


Please visit our website at takedajobs.com

 
 


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