US-MA, Scientist I /Scientist II, DMPK (Modeling and Simulation) 1602904-MZ
Please note that the requirements specified in this posting are the basic qualifications required for the Scientist II position; however, job title will be dependent on the candidate's level of experience in those requirements.
The preclinical translational modeling and simulation group of Takeda Pharmaceuticals in Cambridge MA is seeking a quantitative systems pharmacology modeling & simulation scientist to support oncology drug development by building system models of such as tissue/cell dynamics and intracellular signaling in oncology. The successful candidate will collaborate with Cancer Pharmacology, Chemistry, Translational Medicine, and Clinical Pharmacology to developing mathematical models to understand target, biological pathways, biomarkers and exposure-response relationship of novel antineoplastic agents. The candidate will be also responsible for implementing the right modeling & simulation strategy to assist with lead optimization, establish PK/PD relationships and create mechanistic mathematical models to support project needs. Essential qualifications include in depth understanding of cancer biology and numerical methods, hands-on experience with modeling and simulation software, and ability to clearly present modeling and simulation findings.
EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:
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