Posted to MedZilla on 3/26/2017

Takeda Pharmaceuticals

US-CA, Senior Scientist, Immunology 1602246-MZ



The Immunology Sr. Scientist colleague develops and performs independent scientific research of moderate scope and complexity with limited supervision. The candidate will serve as a technical leader for TCAL Immunology and help direct research and target discovery efforts.


  • Design, develop, and validate relevant in vitro and vivo models for Immunology and GI therapeutic areas.
  • Establish cellular models of disease using patient tissue and cells.
  • Establish innovative pharmacodynamic and efficacy models.
  • Contribute to the development of new translatable disease models, explore disease mechanisms and mechanism of drug action, demonstrating proof of concept for novel therapeutic targets.
  • Assume team member representation at project teams. Colleague will actively participate in both departmental and cross-departmental interactions.
  • Deliver decisional datasets to facilitate selection of disease settings, discovery and validation of biomarkers.
  • Plan, implement and manage internal and external pre-clinical activities and interactions to deliver key experimental studies to support drug candidates in discovery research.
  • Identify and apply novel technology and expertise to enhance drug discovery research programs.
  • Respond quickly to information learned from ongoing studies and provide input to drug discovery and development management to guide program direction and prioritization.
  • Present results both written and verbal and deliver completed reports within a multidisciplinary team environment.
  • Key responsibilities include compound formulation, preliminary safety assessment and assessments of efficacy and PK/PD for drug candidates tested alone or in combinations. He/She will closely collaborate/interact with other scientists from Leads Discovery Biology, Medicinal Chemistry, Structural Biology and Analytical Chemistry.
  • Diligently performs assigned lab and company responsibilities.
  • Maintains concise, accurate, and comprehensible written records as per Takeda California.



  • PhD or equivalent with 4+ relevant years experience OR MS / MA with 14+ years OR BS / BA with 16+ years
  • Has demonstrated independent thought/creativity in science.
  • In vivo pharmacology technical proficiency.
  • Experience with mucosal immunology preferred.
  • Able to present work formally to internal governance bodies
  • Able to convey ideas in an experimentally detailed yet scientifically concise manner
  • Good communication skills
  • Good multitasking skills
  • Willing to work flexible hours

  • While performing the duties of this job, the colleague is regularly required to use hands to handle animals, palpate tissues/objects, use surgical tools, or controls, and to reach with hands or arms.
  • The colleague must lift or move up to 10 pounds on a regular basis in the course of daily activities.
  • Ability to drive to or fly to various meetings, or CRO sites including overnight trips.

we are driven to improve people's lives

Takeda is an EEO employer of minorities, women, disabled, protected veterans. For more information, visit

No Phone Calls or Recruiters Please.



Please visit our website at


* If a direct employer requests that you go to their web site and complete your application there in order to be
  considered, please do so. Applications for all positions are subject to each employer's specific requirements.