Posted to MedZilla on 8/19/2017


ProClinical

United States, Vice President Research and Development SC_KD_13147-MZ


 
 

ProClinical is currently seeking a PhD-level individual for the role of Vice President of R&D for an innovative Biotechnology company based in Connecticut, US on a permanent basis. This biotech is a teamwork-driven, dynamic and energetic group, that seek an individual for this position who will share their core philosophy of innovative, relentless and milestone-driven drug development.

Job Overview:

We are looking to fill this senior level position with someone who can direct our drug development from early stage activity assessment through to clinical trials. These peptide-drug conjugates initially will be tested in vitro in assays using recombinant proteins, followed by testing for functional activity in cell-based assays, and then finally in vivo in mice. Extensive PK/PD and toxicology studies will be performed in parallel. The pace will be brisk, with a plan for Phase I trial(s) within approximately 3-4 years. Experience in the management of team(s) focused on drug development in the biotechnology or pharmaceutical industry is required. In the first year, a major priority will be to identify molecules which target one of five key DNA repair proteins, determine suitable sites for linker attachment, and then test their activity in vitro and in vivo. Considerations of "freedom-to-operate" and intellectual property will weigh heavily in the decision(s) to pursue various leads. He/she will be managing a group of biologists and chemists, while actively creating a development plan to bring leads from early development into the clinic. Additionally, this position will interact closely with a team of medicinal chemistry, regulatory and clinical development consultants, as well as the scientific advisory board (SAB).

Skills and Requirements:

  • Ph.D. in biology or chemistry, Antibody Drug Conjugate or
  • Peptide Drug Conjugate development experience
  • Significant experience in bringing oncology drugs from early stage development through clinical trials.

To Apply:

Please click on the Apply button. Please include a short note outlining why you are interested in the role and why you think you are suitable.
In case you have difficulty in applying or if you have any questions, please call Kaye Dunleavy on +1 646 367 2646 or upload your resume on our website - www.proclinical.com.
A full job description is available on request.
ProClinical is a specialist employment agency and recruitment business, providing job opportunities within major pharmaceutical, biopharmaceutical, biotechnology and medical device companies. 


Please visit our website at www.proclinical.com

 
 


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